Urolithiasis accounts for 15% to 23% of cases of feline lower urinary tract disease (FLUTD), with struvite uroliths occurring more frequently, followed by calcium oxalate, ammonium urate, cystine, and xanthine calculi. In this clinical evaluation, we tested the efficacy of a commercially available nutraceutical diet in 33 cats affected by struvite uroliths. Results clearly indicated a significant urine color, turbidity, pH, RBC, WBC, weight and proteins decrease (***p < 0.001, *p < 0.05), and a significant decrease of struvite uroliths in all treated cats. The nutraceutical diet enriched by botanicals, such as, Hieracium pilosella, Urtica dioica, Lespedeza spp, Vaccinium macrocarpon, Taraxacum officinale formulated with DL-methionine, and a controlled addition of minerals and amino acids resulted particularly effective for struvite uroliths management. This work can pave the way for a new, safe, and long lasting natural approach to treat struvite uroliths.
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